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Symptoms appear several months after excessive doses of vitamin D are administered. A mutation of the CYP24A1 gene can lead to a reduction in the degradation of vitamin D and thus to vitamin toxicity without high oral intake (see Vitamin D: Excess). Symptoms of vitamin D toxicity may include the following: [2] Dehydration; Vomiting; Diarrhea
Treatment involves an initial high-dosage treatment phase until the required serum levels are reached, followed by the maintenance of the acquired levels. The lower the 25(OH)D serum concentration is before treatment, the higher the dosage that is needed to quickly reach an acceptable serum level. [63]
William Kaufman published articles in the 1940s that detailed his treatment of arthritis with frequent, high doses of niacinamide. [18] Rudolf Altschul and Abram Hoffer applied large doses of the immediate release form of niacin (Vitamin B 3) to treat hypercholesterolemia.
Effects of low dose vs. high dose vitamin D In this double-blind, randomized controlled trial (RCT), researchers examined 221 adults ages 65 years or older who had BMIs over 25 and were considered ...
An estimated third of Americans 60 and older take the supplements and more than 10 million blood tests for vitamin D levels are performed annually -- despite years of controversy over whether the ...
Each of these high-potency softgels delivers 5,000 IU of vitamin D3, making them a fantastic option for those looking to boost their vitamin D levels significantly. "With 125 percent of the ...