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Open Chemistry Project: BEDtools "Genome arithmetic"—manipulation of coordinate sets and the extraction of sequences from a BED file. Linux: MIT: QuinlanLab, University of Utah: Bioclipse: Visual platform for chemo- and bioinformatics based on the Eclipse Rich Client Platform (RCP) Linux, macOS, Windows [1] Eclipse Public: The Bioclipse ...
Uses adaptative seeds and copes more efficiently with repeat-rich sequences (e.g. genomes). For example: it can align reads to genomes without repeat-masking, without becoming overwhelmed by repetitive hits. Yes Yes Yes Yes Free, GPL [46] 2011 MAQ Ungapped alignment that takes into account quality scores for each base. Free, GPL: mrFAST, mrsFAST
This server includes many bioinformatics tools that are widely useful in many areas of genomics research. Users can create logins, and save histories, workflows, and datasets on the server. These saved items can also be shared with others. As open-source software that can be downloaded, installed and customized to address specific needs. [20]
Open source software provides a platform for computational biology where everyone can access and benefit from software developed in research. PLOS cites [citation needed] four main reasons for the use of open source software: Reproducibility: This allows for researchers to use the exact methods used to calculate the relations between biological ...
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The source code for the package is distributed freely and compiled binaries are available for Linux, macOS and Windows platforms. As of 2017, the Genome Biology paper describing the original Bowtie method has been cited more than 11,000 times. [3] Bowtie is open-source software and is currently maintained by Johns Hopkins University.
GMOD: GMOD (Generic Model Organism Database) is a collection of open-source tools for building and sharing genome databases. It provides a framework for integrating genomic data with other biological data types, such as proteomics and metabolomics, and allows for the sharing of data and analysis with collaborators.
Ensembl Genomes: provides genome-scale data for bacteria, protists, fungi, plants and invertebrate metazoa, through a unified set of interactive and programmatic interfaces (using the Ensembl software platform) FlyBase: genome of the model organism Drosophila melanogaster; Gene Disease Database