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  2. Olaparib - Wikipedia

    en.wikipedia.org/wiki/Olaparib

    Olaparib acts as an inhibitor of the enzyme poly ADP ribose polymerase (PARP), and is termed a PARP inhibitor. BRCA1/2 mutations may be genetically predisposed to development of some forms of cancer, and may be resistant to other forms of cancer treatment. However, these cancers sometimes have a unique vulnerability, as the cancer cells have ...

  3. PARP inhibitor - Wikipedia

    en.wikipedia.org/wiki/PARP_inhibitor

    PARP inhibitors are a call of drugs that are a group of pharmacological inhibitors of the enzyme poly ADP ribose polymerase (PARP), which plays a role in repairing DNA in damaged cells. Medical uses of these drugs include the treatment of heritable cancers . [ 1 ]

  4. Category:PARP inhibitors - Wikipedia

    en.wikipedia.org/wiki/Category:PARP_inhibitors

    Download as PDF; Printable version; In other projects Wikidata item; ... Pages in category "PARP inhibitors" The following 10 pages are in this category, out of 10 ...

  5. Cancer treatment - Wikipedia

    en.wikipedia.org/wiki/Cancer_treatment

    Cancer treatments are a wide range of treatments available for the many different types of cancer, with each cancer type needing its own specific treatment. [1] Treatments can include surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy including small-molecule drugs or monoclonal antibodies, [2] and PARP inhibitors such as olaparib. [3]

  6. Veliparib - Wikipedia

    en.wikipedia.org/wiki/Veliparib

    Veliparib (ABT-888) [1] is a potential anti-cancer drug acting as a PARP inhibitor.It kills cancer cells by blocking a protein called PARP, thereby preventing the repair of DNA or genetic damage in cancer cells and possibly making them more susceptible to anticancer treatments.

  7. Breast cancer management - Wikipedia

    en.wikipedia.org/wiki/Breast_cancer_management

    Staging breast cancer is the initial step to help physicians determine the most appropriate course of treatment. As of 2016, guidelines incorporated biologic factors, such as tumor grade, cellular proliferation rate, estrogen and progesterone receptor expression, human epidermal growth factor 2 (HER2) expression, and gene expression profiling into the staging system.

  8. Fluorouracil - Wikipedia

    en.wikipedia.org/wiki/Fluorouracil

    Fluorouracil has been given systemically for anal, breast, colorectal, oesophageal, stomach, pancreatic and skin cancers (especially head and neck cancers). [12] It has also been given topically (on the skin) for actinic keratoses, skin cancers and Bowen's disease [12] (a type of cutaneous squamous-cell carcinoma), and as eye drops for treatment of ocular surface squamous neoplasia. [13]

  9. Capecitabine - Wikipedia

    en.wikipedia.org/wiki/Capecitabine

    Capecitabine, sold under the brand name Xeloda among others, is a anticancer medication used to treat breast cancer, gastric cancer and colorectal cancer. [3] For breast cancer it is often used together with docetaxel. [4]

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