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  2. Adenosine A1 receptor - Wikipedia

    en.wikipedia.org/wiki/Adenosine_A1_receptor

    A 1 receptors are implicated in sleep promotion by inhibiting wake-promoting cholinergic neurons in the basal forebrain. [6] A 1 receptors are also present in smooth muscle throughout the vascular system. [7] The adenosine A 1 receptor has been found to be ubiquitous throughout the entire body. [citation needed]

  3. Adenosine receptor - Wikipedia

    en.wikipedia.org/wiki/Adenosine_receptor

    Caffeine keeps you awake by blocking adenosine receptors. Each type of adenosine receptor has different functions, although with some overlap. [3] For instance, both A 1 receptors and A 2A play roles in the heart, regulating myocardial oxygen consumption and coronary blood flow, while the A 2A receptor also has broader anti-inflammatory effects throughout the body. [4]

  4. Purinergic signalling - Wikipedia

    en.wikipedia.org/wiki/Purinergic_signalling

    The activation of the adenosine A1 receptor is required for osteoclast differentiation and function, whereas the activation of the adenosine A2A receptor inhibits osteoclast function. The other three adenosine receptors are involved in bone formation.

  5. Adenosine - Wikipedia

    en.wikipedia.org/wiki/Adenosine

    The A 1 receptors couple to G i/o and decrease cAMP levels, while the A 2 adenosine receptors couple to G s, which stimulates adenylate cyclase activity. In addition, A 1 receptors couple to G o , which has been reported to mediate adenosine inhibition of Ca 2+ conductance, whereas A 2B and A 3 receptors also couple to G q and stimulate ...

  6. Adenosinergic - Wikipedia

    en.wikipedia.org/wiki/Adenosinergic

    Adenosinergic means "working on adenosine". An adenosinergic agent (or drug) is a chemical which functions to directly modulate the adenosine system in the body or brain. Examples include adenosine receptor agonists, adenosine receptor antagonists (such as caffeine), and adenosine reuptake inhibitors.

  7. Trump and Musk unleash a new kind of chaos on Washington

    www.aol.com/news/trump-musk-unleash-kind-chaos...

    A government shutdown could have unpredictable political consequences since it would hurt many Americans, potentially including seniors and veterans who rely on government help, and could also ...

  8. Adenosine A2A receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Adenosine_A2A_Receptor...

    A 2A receptor antagonists may prevent hepatic cirrhosis, and pentoxifylline may inhibit phosphodiesterase and provide renal protection. [6]The A 2A receptor antagonists may be used for treatment of attention deficit hyperactivity disorder (), because of the receptors ability to regulate neurotransmission in the basal ganglia and cortex, particularly dopaminergic and glutamatergic signaling.

  9. Orange Cat Determined to Hunt Bug on Ceiling Is a Lesson in ...

    www.aol.com/orange-cat-determined-hunt-bug...

    The orange cat in this video is desperate to catch a bug hanging out on the ceiling of his home—so desperate, in fact, that he may be taking his very life in his hands.