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  2. Elevated alpha-fetoprotein - Wikipedia

    en.wikipedia.org/wiki/Elevated_alpha-fetoprotein

    Rare AFP-secreting tumor types include carcinoma in a mixed Müllerian tumor. [14] The Sertoli-Leydig cell tumor, which itself is rare, rarely secretes AFP. [15] In Wilms tumor AFP is rarely elevated, but when it is elevated it may serve as a marker of disease progression or recurrence. [16]

  3. Alpha-fetoprotein - Wikipedia

    en.wikipedia.org/wiki/Alpha-fetoprotein

    Very high AFP levels may be subject to hooking (see Tumor marker), which results in the level being reported significantly lower than the actual concentration. [29] This is important for analysis of a series of AFP tumor marker tests, e.g. in the context of post-treatment early surveillance of cancer survivors, where the rate of decrease of AFP ...

  4. Tumor marker - Wikipedia

    en.wikipedia.org/wiki/Tumor_marker

    A tumor marker is a biomarker that can be used to indicate the presence of cancer or the ... Alpha fetoprotein (AFP) germ cell tumor, hepatocellular carcinoma [9] CA15-3:

  5. AFP-L3 - Wikipedia

    en.wikipedia.org/wiki/AFP-L3

    Usefulness of lens culinaris agglutinin A-reactive fraction of alpha-fetoprotein (AFP-L3) as a marker of distant metastasis from hepatocellular carcinoma. Yamashiki, N., et al., Oncology Reports, 6, 1229–1232, 1999. Relationship between lens culinaris agglutinin reactive alpha-fetoprotein and biological features of hepatocellular carcinoma.

  6. Fetal protein - Wikipedia

    en.wikipedia.org/wiki/Fetal_protein

    In pregnant people AFP levels rise at 14 weeks until 32 weeks, and range between 10 and 150 ng/mL in the middle of gestation. This is why AFP can be used alongside other tests as a tumor marker protein in adults. [12] AFP is a single polypeptide chain with a half-life of 4–5 days.

  7. Oncofetal antigen - Wikipedia

    en.wikipedia.org/wiki/Oncofetal_antigen

    These proteins are often measurable in the blood of individuals with cancer and may be used to both diagnose and follow treatment of the tumors. One example of an oncofetal antigen is alpha-fetoprotein , which is produced by hepatocellular carcinoma and some germ cell tumors .

  8. Teratoma - Wikipedia

    en.wikipedia.org/wiki/Teratoma

    Of special concern is the secretion of alpha-fetoprotein (AFP); under some circumstances, AFP can be used as a diagnostic marker specific for the presence of yolk sac cells within the teratoma. These cells can develop into a frankly malignant tumor known as yolk sac tumor or endodermal sinus tumor.

  9. Embryonal carcinoma - Wikipedia

    en.wikipedia.org/wiki/Embryonal_carcinoma

    There may be elevations in serum human chorionic gonadotropin (hCG) and alpha fetoprotein (AFP) levels but it would be in association with other tumors, (e.g. yolk sac tumor) because they themselves do not produce the serum markers. [4] At surgery, there is extension of the tumour beyond the ovary in forty percent of cases.