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Women should speak to their doctor or healthcare professional before starting or stopping any medications while pregnant. [1] Drugs taken in pregnancy including over-the counter-medications, prescription medications, nutritional supplements, recreational drugs, and illicit drugs may cause harm to the mother or the unborn child.
Opioid drugs are used for various reasons during pregnancy, with pain being a frequent issue. Conditions like pelvic and lower back pain, occurring in around 68 to 72% of pregnancies, are commonly treated with these medications. [2] [3] [4] Moreover, other sources of pain like muscle aches, migraines, and joint pain are commonly reported during ...
The use of alcohol during pregnancy occurs at different rates across the world, potentially due to various cultural differences and legislation. The five countries with the highest prevalence of alcohol use during pregnancy are Ireland (60%), Belarus (47%), Denmark (46%), the UK (41%), and the Russian Federation (37%). [29]
Post-acute withdrawal syndrome (PAWS) is a hypothesized set of persistent impairments that occur after withdrawal from alcohol, [1] [2] opiates, benzodiazepines, antidepressants, and other substances. [3] [4] [5] Infants born to mothers who used substances of dependence during pregnancy may also experience a PAWS.
Nonpharmacological interventions are usually prioritized for the treatment of infants with NAS, but for those experiencing severe opioid withdrawal then the use of medications is to be considered. [29] Medications are used to minimize clinical signs of withdrawal including fever, seizures, and weight loss or dehydration. [33]
Oxazepam, as with other benzodiazepine drugs, can cause tolerance, physical dependence, addiction, and benzodiazepine withdrawal syndrome. Withdrawal from oxazepam or other benzodiazepines often leads to withdrawal symptoms which are similar to those seen during alcohol and barbiturate withdrawal. The higher the dose and the longer the drug is ...
Prenatal cocaine exposure (PCE), theorized in the 1970s, occurs when a pregnant woman uses cocaine including crack cocaine and thereby exposes her fetus to the drug.Babies whose mothers used cocaine while pregnant supposedly have increased risk of several different health issues during growth and development and are colloquially known as crack babies.
The use of alprazolam during pregnancy is associated with congenital abnormalities, [9] [61] and use in the last trimester may cause fetal drug dependence and withdrawal symptoms in the post-natal period as well as neonatal flaccidity and respiratory problems.