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Continued cigarette smoking negatively impacts limited-stage small cell lung cancer survival. All clinicians and care providers should strongly encourage smoking cessation at the diagnosis of limited stage small cell lung cancer. Comparing to continued smokers, patients who quit at or after diagnosis lower the risk of death by 45%. [28]
Chemotherapy for NSCLC usually includes combination of two drugs (chemotherapy doublet), with one of the agents is cisplatin or carboplatin. In 2002, Schiller at al. published in the New England Journal of Medicine, a study that compared four chemotherapy regimens for advanced NSCLC, cisplatin and paclitaxel, cisplatin and gemcitabine, cisplatin and docetaxel, and carboplatin and paclitaxel. [14]
Targeted therapy of lung cancer refers to using agents specifically designed to selectively target molecular pathways responsible for, or that substantially drive, the malignant phenotype of lung cancer cells, and as a consequence of this (relative) selectivity, cause fewer toxic effects on normal cells.
One small study found that lung cancer patients didn’t start treatment for an average of 138 days after their first symptoms began. That’s not lost on Lin. That’s not lost on Lin.
Lung cancer risk is influenced by environmental exposure, namely cigarette smoking, as well as occupational risks in mining, shipbuilding, petroleum refining, and occupations that involve asbestos exposure. [98] People who have smoked cigarettes account for 85–90% of lung cancer cases, and 15% of smokers develop lung cancer. [98]
Martell estimated that a carcinogenic radiation dose of 80–100 rads is delivered to the lung tissue of most smokers who die of lung cancer. [ 229 ] [ 230 ] [ 231 ] Smoking an average of 1.5 packs per day gives a radiation dose of 60-160 mSv /year, [ 232 ] [ 233 ] compared with living near a nuclear power station (0.0001 mSv/year) [ 234 ...
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