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In addition to producing feminization, estrogens have antigonadotropic effects, suppressing testosterone and other gonadal sex hormones. [ 15 ] [ 29 ] [ 30 ] Levels of estradiol of 200 pg/mL and above suppress testosterone levels by about 90%, while estradiol levels of 500 pg/mL and above suppress testosterone levels by about 95%, or to an ...
Gender-affirming hormone therapy (GAHT), also called hormone replacement therapy (HRT) or transgender hormone therapy, is a form of hormone therapy in which sex hormones and other hormonal medications are administered to transgender or gender nonconforming individuals for the purpose of more closely aligning their secondary sexual characteristics with their gender identity.
Target ranges for hormone levels in hormone therapy for transgender women; Source Place Estradiol, total Testosterone, total Refs Endocrine Society: United States: 100–200 pg/mL
However, this procedure carries a risk of impairing a trans woman's voice forever. Since estrogen alone does not alter a person's vocal range or pitch, some people take the risk that comes along with voice feminization surgery. Other options, like voice feminization lessons, are available to people wishing to speak with less masculine mannerisms.
The use of high-dose estrogen therapy in breast cancer has mostly been superseded by antiestrogen therapy due to the improved safety profile of the latter. [17] High-dose estrogen therapy was the standard of care for the palliative treatment of breast cancer in women up to the late 1970s or early 1980s. [18
Tyrrell told cops he went hiking Dec. 21, stopped at the fridge and took something out of it, the state police said. This distinctive yoga mat was found near the corpse. New Jersey State Police
Lady Gabriella Kingston’s husband took his own life after suffering an adverse reaction to an antidepressant medication prescribed by his doctor, a coroner has ruled.. Thomas Kingston, who ...
The author (left) with her "I Voted" sticker on Nov. 5, 2024, and Donald Trump (right), who will begin his second White House term in January.