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Sjögren's syndrome can damage vital organs, with symptoms that may plateau or worsen, or go into remission, as with other autoimmune diseases. Some people may experience only the mild symptoms of dry eyes and mouth, while others have symptoms of severe disease. Many patients can treat problems symptomatically.
This article provides a list of autoimmune diseases. These conditions, where the body's immune system mistakenly attacks its own cells, affect a range of organs and systems within the body. Each disorder is listed with the primary organ or body part that it affects and the associated autoantibodies that are typically found in people diagnosed ...
Henrik Samuel Conrad Sjögren (UK: / ˈ ʃ ɜː ɡ r ɛ n /, US: / ˈ ʃ oʊ ɡ r ɛ n /, [1] Swedish: [ˈɧø̂ːɡreːn]; [2] 23 July 1899, Köping – 17 September 1986, Lund) [3] was a Swedish ophthalmologist best known for describing the eponymous condition Sjögren syndrome. Sjögren received his medical degree in Stockholm in 1927.
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Henrik Sjögren (1899–1986), Swedish ophthalmologist for whom Sjögren's syndrome was named, an autoimmune disorder leading to dry eyes and mouth; Hjalmar Sjögren, Swedish geologist and mineralogist; John C. Sjogren, United States Army soldier who received the Medal of Honor in World War II; John M. Sjogren American film director
The estimated community prevalence, which takes into account the observation that many people have more than one autoimmune disease, was 4.5% overall, with 2.7% for males and 6.4% for females. [74] A 2024 estimate was that 1 in 15 people in the U.S. had at least one autoimmune disease. [76]
Most autoimmune diseases are sex-related; as a whole, women are much more likely to develop autoimmune disease than men. Being female is the single greatest risk factor for developing autoimmune disease than any other genetic or environmental risk factor yet discovered.
While persons with autoimmune diseases have a high likelihood of having dry eyes, most persons with dry eyes do not have an autoimmune disease. [16] Instances of Sjögren syndrome and keratoconjunctivitis sicca associated with it are present much more commonly in women, with a ratio of 9:1.