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5-MeO-DMT (5-methoxy-N,N-dimethyltryptamine), also known as O-methylbufotenin or mebufotenin (INN Tooltip International Nonproprietary Name), is a naturally occurring psychedelic of the tryptamine family. [5] [1] [4] [2] It is found in a wide variety of plant species, and is also secreted by the glands of at least one toad species, the Colorado ...
The Colorado River toad can grow to about 190 millimetres (7.5 in) long and is the largest toad in the United States apart from the non-native cane toad (Rhinella marina). It has a smooth, leathery skin and is olive green or mottled brown in color. Just behind the large golden eye with horizontal pupil is a bulging kidney-shaped parotoid gland.
In contrast to peripheral administration, intracerebroventricular injection of bufotenin in animals produces robust psychedelic-like behavioral effects similar to those of other serotonergic psychedelics like 5-MeO-DMT. [39] In addition, 5-MeO-DMT, the O-methylated analogue of bufotenin, which has much greater lipophilicity, is readily able to ...
5-MeO-DMT is a potent and fast-acting psychedelic, which is naturally produced by the Sonoran Desert toad as well as some species of plants. Its short duration –from 20 minutes to one hour– is ...
Beans: 5-MeO-DMT. Up to 12.4% bufotenin. [33] DMT Psychedelic: There have been reports of active use of vilca by Wichi shamans, under the name hatáj. [34] Yopo: Anadenanthera peregrina: Beans: 5-MeO-DMT. Up to 7.4% bufotenin. [33] DMT Psychedelic: Archaeological evidence of insufflation use within the period 500-1000 AD, in northern Chile, has ...
Bufotoxins can contain 5-MeO-DMT, bufagins, bufalin, bufotalin, bufotenin, bufothionine, dehydrobufotenine, epinephrine, norepinephrine, and serotonin. Some authors have also used the term bufotoxin to describe the conjugate of a bufagin with suberylarginine. [4] The toxic substances found in toads can be divided by chemical structure in two ...
Greening's frog (Corythomantis greeningi) Unknown injectable venom [3] Brazil Panamanian golden frog (Atelopus zeteki) Zetekitoxin AB, Bufadienolide: Central Panama. American toad (Anaxyrus americanus) Bufotoxin: eastern United States and Canada. Colorado River toad (Incilius alvarius) 5-MeO-DMT, Bufotenin
P. clavata (violescent sea-whip). Colorado River toad (Sonoran Desert toad or Bufo alvarius): 5-MeO-DMT and bufotenin; Asiatic toad and certain tree frogs (Osteocephalus taurinus, Osteocephalus oophagus, and Osteocephalus langsdorfii): bufotenin