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  2. Alcohol intoxication - Wikipedia

    en.wikipedia.org/wiki/Alcohol_intoxication

    Alcohol intoxication leads to negative health effects due to the recent drinking of large amount of ethanol (alcohol). [ 6 ] [ 20 ] When severe it may become a medical emergency . Some effects of alcohol intoxication, such as euphoria and lowered social inhibition , are central to alcohol's desirability.

  3. Alcohol and health - Wikipedia

    en.wikipedia.org/wiki/Alcohol_and_health

    Alcohol is known to potentiate the insulin response of the human body to glucose, which, in essence, "instructs" the body to convert consumed carbohydrates into fat and to suppress carbohydrate and fat oxidation. [63] [64] Ethanol is directly processed in the liver to acetyl CoA, the same

  4. Alcohol (drug) - Wikipedia

    en.wikipedia.org/wiki/Alcohol_(drug)

    Disulfiram inhibits the enzyme acetaldehyde dehydrogenase, which in turn results in buildup of acetaldehyde, a toxic metabolite of ethanol with unpleasant effects. The medication or drug is commonly used to treat alcohol use disorder, and results in immediate hangover-like symptoms upon consumption of alcohol, this effect is widely known as ...

  5. Alcohol tolerance - Wikipedia

    en.wikipedia.org/wiki/Alcohol_tolerance

    To engage in alcohol consumption and the development of an alcohol use disorder appear to be common to primates, and is not a specific human phenomenon. [9] Humans have access to alcohol in far greater quantity than non-human primates, and the availability increased, particularly with the development of agriculture. [ 10 ]

  6. Alcohol (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Alcohol_(chemistry)

    Ethanol is less acutely toxic. [27] All alcohols are mild skin irritants. [25] Methanol and ethylene glycol are more toxic than other simple alcohols. Their metabolism is affected by the presence of ethanol, which has a higher affinity for liver alcohol dehydrogenase. In this way, methanol will be excreted intact in urine. [28] [29] [30]

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  8. Pharmacology of ethanol - Wikipedia

    en.wikipedia.org/wiki/Pharmacology_of_ethanol

    The reaction from ethanol to carbon dioxide and water proceeds in at least 11 steps in humans. C 2 H 6 O (ethanol) is converted to C 2 H 4 O (acetaldehyde), then to C 2 H 4 O 2 (acetic acid), then to acetyl-CoA. Once acetyl-CoA is formed, it is free to enter directly into the citric acid cycle (TCA) and is converted to 2 CO 2 molecules in 8 ...

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