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Cypher is a brand of drug-eluting coronary stent from Cordis Corporation, a Cardinal Health company. During a balloon angioplasty, the stent is inserted into the artery to provide a "scaffold" to open the artery.
However, the stent has not completely done away with restenosis after angioplasty, and improved procedures continue to be sought. The drug-eluting stent, which releases chemicals that inhibit restenosis, has shown marked success and seems to be replacing the bare-metal stent in America, though Europeans have resisted the change due to the expense.
Angioplasty is used to treat venous stenosis affecting dialysis access, with drug-coated balloon angioplasty proving to have better 6 month and 12 month patency than conventional balloon angioplasty. [13] Angioplasty is occasionally used to treat residual subclavian vein stenosis following decompression surgery for thoracic outlet syndrome. [14]
A drug-eluting stent (DES) is a small mesh tube that is placed in the arteries to keep them open in the treatment of vascular disease.The stent slowly releases a drug to block cell proliferation (a biological process of cell growth and division), thus preventing the arterial narrowing that can occur after stent implantation.
Coronary stents are placed during a coronary angioplasty.The most common use for coronary stents is in the coronary arteries, into which a bare-metal stent, a drug-eluting stent, a bioabsorbable stent, a dual-therapy stent (combination of both drug and bioengineered stent), or occasionally a covered stent is inserted.
Despite its reduced rates of restenosis compared to plain old balloon angioplasty, it still had high rates of stent thrombosis and required a high dosage of blood thinners. [4] This led to the development of drug-eluting stents to act as local drug delivery and vascular scaffold platform to reduce in-stent restenosis. [4]
After the FDA has banned red dye No.3, you may be wondering which drinks and candies contain it. Here's the full list—plus, when it'll be removed from shelves.
Polymer implant eluting drugs. Drug eluting implants encompass a wide range of bioactive implants that can be placed in or near a tissue to provide a controlled, sustained or on demand release of drug while overcoming barriers associated with traditional oral and intravenous drug administration, such as limited bioavailability, metabolism, and toxicity. [1]