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Almost half of those infected with giardiasis remain asymptomatic. For those who do experience symptoms, they usually appear 1 to 2 weeks after infection. Common symptoms include abdominal pain, nausea, and bloating, along with large, watery, foul-smelling, and greasy stools.
Less common symptoms include vomiting and blood in the stool. [1] Symptoms usually begin one to three weeks after exposure and, without treatment, may last two to six weeks or longer. [4] Giardiasis usually spreads when Giardia duodenalis cysts within faeces contaminate food or water that is later consumed orally. [1]
Giardia (/ dʒ iː ˈ ɑːr d i ə / or / ˈ dʒ ɑːr d i ə /) is a genus of anaerobic flagellated protozoan parasites of the phylum Metamonada that colonise and reproduce in the small intestines of several vertebrates, causing the disease giardiasis. Their life cycle alternates between a swimming trophozoite and an infective, resistant cyst.
Gastrointestinal conditions include inflammation of the small and/or large intestine, diarrhea/dysentery, abdominal pains, and nausea/vomiting. These symptoms negatively impact nutritional status, including decreased absorption of micronutrients, loss of appetite, weight loss, and intestinal blood loss that can often result in anemia.
Giardiasis is a disease of the small intestine caused by a protist parasite Giardia lamblia. This does not spread but remains confined to the lumen of the small intestine. [47] It can often be asymptomatic, but as often can be indicated by a variety of symptoms. Giardiasis is the most common pathogenic parasitic infection in humans. [48]
The common intestinal parasite Giardia duodenalis (synonyms Giardia lamblia, G. intestinalis) was once considered to be a descendant of a protist lineage that predated the emergence of meiosis and sex.
The gut-associated lymphoid tissue lies throughout the intestine, covering an area of approximately 260–300 m 2. [5] In order to increase the surface area for absorption, the intestinal mucosa is made up of finger-like projections (), covered by a monolayer of epithelial cells, which separates the GALT from the lumen intestine and its contents.
No one knows how D. fragilis is spread; one possibility is from swallowing contaminated water or food. Many people who are infected with this parasite show no signs of being infected. Sometimes the infection can be observed; the most common symptoms include diarrhea, stomach pains, loss of appetite, nausea, and fatigue. [11]