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  2. Opioid - Wikipedia

    en.wikipedia.org/wiki/Opioid

    Long-term opioid use can cause opioid-induced hyperalgesia, which is a condition in which the patient has increased sensitivity to pain. [101] All of the opioids can cause side effects. [70] Common adverse reactions in patients taking opioids for pain relief include nausea and vomiting, drowsiness, itching, dry mouth, dizziness, and constipation.

  3. Opioid use disorder - Wikipedia

    en.wikipedia.org/wiki/Opioid_use_disorder

    Long-term opioid use occurs in about 4% of people following their use for trauma or surgery-related pain. [20] In the United States, most heroin users begin by using prescription opioids that may also be bought illegally. [21] [22] People with opioid use disorder are often treated with opioid replacement therapy using methadone or buprenorphine ...

  4. Opiate - Wikipedia

    en.wikipedia.org/wiki/Opiate

    While the full synthesis of opioids from naphthoquinone (Gates synthesis) or other simple organic starting materials is possible, they are tedious and uneconomical processes. Therefore, most of the opiate-type analgesics in use today are either extracted from Papaver somniferum or synthesized from those opiates, especially thebaine. [10]

  5. Oxycodone - Wikipedia

    en.wikipedia.org/wiki/Oxycodone

    In the United States, more than 12 million people use opioid drugs recreationally. [123] The U.S. Department of Health and Human Services estimates that about 11 million people in the U.S. consume oxycodone in a non-medical way annually. [124] Opioids were responsible for 49,000 of the 72,000 drug overdose deaths in the U.S. in 2017. [125]

  6. Opioid epidemic - Wikipedia

    en.wikipedia.org/wiki/Opioid_epidemic

    The opioid epidemic, also referred to as the opioid crisis, is the rapid increase in the overuse, misuse/abuse, and overdose deaths attributed either in part or in whole to the class of drugs called opiates/opioids since the 1990s. It includes the significant medical, social, psychological, demographic and economic consequences of the medical ...

  7. Prescription drug addiction - Wikipedia

    en.wikipedia.org/wiki/Prescription_Drug_Addiction

    Prescription drug addiction is the chronic, repeated use of a prescription drug in ways other than prescribed for, including using someone else’s prescription. [3] [4] A prescription drug is a pharmaceutical drug that may not be dispensed without a legal medical prescription.

  8. List of opioids - Wikipedia

    en.wikipedia.org/wiki/List_of_opioids

    Carbonate derivatives of 14β-hydroxycodeine "viz., 14β-hydroxy-6-O-(methoxycarbonyl)codeine, 6-O-methoxycarbonyl-14β-(methoxycarbonyloxy)codeine, and 14β-acetoxy-6-O-methoxy-carbonylcodeine, potential substrates for ring C modification in morphinane (sic) alkaloids, were synthesized for the first time."

  9. Opioid overdose - Wikipedia

    en.wikipedia.org/wiki/Opioid_overdose

    An opioid overdose is toxicity due to excessive consumption of opioids, such as morphine, codeine, heroin, fentanyl, tramadol, and methadone. [3] [5] This preventable pathology can be fatal if it leads to respiratory depression, a lethal condition that can cause hypoxia from slow and shallow breathing. [3]