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More than 10% of people taking linaclotide have diarrhea. Between 1% and 10% of people have decreased appetite, dehydration, low potassium, dizziness when standing up too quickly , nausea, vomiting, urgent need to defecate, fecal incontinence, and bleeding in the colon, rectum, and anus.
Plecanatide has been shown to be safe and effective. It has shown to be at least equally as effective as its main competitor, linaclotide (brand name Linzess), but has been shown to have a lower rate of diarrhea as an adverse drug reaction. [10]
Electrolyte solutions, while not true antidiarrheals, are used to replace lost fluids and salts in acute cases.; Bulking agents like methylcellulose, guar gum or plant fibre (bran, sterculia, isabgol, etc.) are used for diarrhoea in functional bowel disease and to control ileostomy output.
If your diarrhea lasts longer than a couple of days, Dr. Ahmad suggests calling your doctor, especially if you also have a fever, dehydration, bloody stool, weight loss, pain, and severe pain.
Diarrhea is defined by the World Health Organization as having three or more loose or liquid stools per day, or as having more stools than is normal for that person. [2] Acute diarrhea is defined as an abnormally frequent discharge of semisolid or fluid fecal matter from the bowel, lasting less than 14 days, by World Gastroenterology ...
Eluxadoline, sold under the brand names Viberzi and Truberzi, [3] is a medication taken by mouth for the treatment of diarrhea and abdominal pain in individuals with diarrhea-predominant irritable bowel syndrome (IBS-D). [4] It was approved for use in the United States in 2015. [5] The drug originated from Janssen Pharmaceutica and was ...