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The oxygen enhancement ratio (OER) or oxygen enhancement effect in radiobiology refers to the enhancement of therapeutic or detrimental effect of ionizing radiation due to the presence of oxygen. This so-called oxygen effect [ 1 ] is most notable when cells are exposed to an ionizing radiation dose .
The best known explanation of the oxygen effect is the oxygen fixation hypothesis developed by Alexander in 1962, [9] which posited that radiation-induced non-restorable or "fixed" nuclear DNA lesions are lethal to cells in the presence of diatomic oxygen. [10] [11] Recent hypotheses include one based on oxygen-enhanced damage from first ...
Oxygen enhancement ratio, effect magnitude of ionizing radiation due to the presence of oxygen Oxygen Evolution Reaction , the formation of oxygen by electrochemical reduction of water Owner’s Equivalent Rent, an economic metric for housing prices often used in the calculation of market baskets
Fraction of inspired oxygen (F I O 2), correctly denoted with a capital I, [1] is the molar or volumetric fraction of oxygen in the inhaled gas. Medical patients experiencing difficulty breathing are provided with oxygen-enriched air, which means a higher-than-atmospheric F I O 2. Natural air includes 21% oxygen, which is equivalent to F I O 2 ...
Oxygen transmission rate (OTR) is the measurement of the amount of oxygen gas that passes through a substance over a given period. It is mostly carried out on non-porous materials, where the mode of transport is diffusion, but there are a growing number of applications where the transmission rate also depends on flow through apertures of some description.
The oxygenation index is a calculation used in intensive care medicine to measure the fraction of inspired oxygen (FiO2) and its usage within the body.. A lower oxygenation index is better - this can be inferred by the equation itself.
As ions' damage is direct, OER (Oxygen Enhancement Ratio) is 1, so the effect of oxygen it is not important. An important approach of hypoxia-related treatment interventions is a procedure called dose painting, in which a higher radiation dose is targeted to hypoxic subvolumes of tumor. [ 37 ]
Oxygen equivalent compares the relative amount of oxygen available for respiration at a variable pressure to that available at SATP.As external respiration depends on the exchange of gases due to partial pressures across a semipermeable membrane and normally occurs at SATP, an oxygen equivalent may aid in recognizing and managing variable oxygen availability during procedures such as ...