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Chitinases (EC 3.2.1.14, chitodextrinase, ... Chitinases production in the human body (known as "human chitinases") may be in response to allergies, ...
Some members of this family, CAZY GH_18, belong to the chitinase class II group which includes chitinase, chitodextrinase and the killer toxin of Kluyveromyces lactis. The chitinases hydrolyse chitin oligosaccharides. Another chitinase II member is the novel gene Chitinase domain-containing protein 1.
Many pathogenesis-related protein families also coincide with groups of human allergens, even though the allergy may have nothing to do with the defense function of the proteins. [5] Grouping these proteins by their sequence features allows for finding potential allergenic proteins from sequenced plant genomes, a field of study dubbed ...
Chitinase domain-containing protein 1 (CHID1) is a highly conserved protein of unknown function located on the short (p) arm of chromosome 11 near the telomere. [5] The protein has 27 introns, which allows for many isoforms of this gene. It has several aliases, the most common of which is Stabilin-1 interacting chitinase-like protein (SI-CLP).
Chitinase-3-like protein 1 (CHI3L1), also known as YKL-40, is a secreted glycoprotein that is approximately 40kDa in size that in humans is encoded by the CHI3L1 gene. [ 5 ] [ 6 ] [ 7 ] The name YKL-40 is derived from the three N-terminal amino acids present on the secreted form and its molecular mass .
On Dec. 12, Cal Yee Farms recalled some of its chocolate and yogurt-covered products, including dark chocolate walnuts, yogurt-coated almonds and butter toffee, amid an allergy alert because they ...
Hevein is the main IgE-binding epitope of the major latex allergen prohevein [4] as are hevein-like protein domains in fruit class I chitinases. [5] Therefore it is a possible cause for allergen cross-reactivity between latex and banana or other fruits like chestnuts or avocadoes. [6]
Interleukin-13 is a central regulator in IgE synthesis, goblet cell hyperplasia, mucus hypersecretion, airway hyperresponsiveness, fibrosis and chitinase up-regulation. [7] It is a mediator of allergic inflammation and different diseases including asthma, [7] and atopic dermatitis. [9]
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