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Ketamine crystals on a glass plate. K-hole is the feeling of getting a high enough dose of ketamine to experience a state of dissociation.This intense detachment from reality is often a consequence of accidental overconsumption of ketamine; however, some users consciously seek out the k-hole as they find the powerful dissociative effects to be quite pleasurable and enlightening.
“Ketamine overdose by itself is exceedingly rare,” said Dr. Siddarth Puri, associate medical director of prevention for the Substance Abuse Prevention and Control division at L.A. County’s ...
Ketamine may partially improve depressive symptoms [19] among people with bipolar depression at 24 hours after treatment, but not three or more days. [66] Potentially, ten more people with bipolar depression per 1000 may experience brief improvement, but not the cessation of symptoms, one day following treatment.
NMDA receptor antagonists induce a state called dissociative anesthesia, marked by catalepsy, amnesia, and analgesia. [1] Ketamine is a favored anesthetic for emergency patients with unknown medical history and in the treatment of burn victims because it depresses breathing and circulation less than other anesthetics.
Current ketamine treatment is in the form of a nasal spray (in the form of esketamine) or injection. Both require that the patient stays in the clinic to be monitored for around 2 hours ...
It concluded that Perry died from the “acute effects of ketamine” while contributing factors included “drowning, coronary artery disease and the effects of buprenorphine” – which is ...
The researchers looked at data on 424 people with treatment-resistant depression who were treated between November 2017 and May 2021 at three ketamine infusion clinics in Virginia that specialize ...
Ketamine-assisted psychotherapy (KAP) is the use of prescribed doses of ketamine as an adjunct to psychotherapy sessions. KAP shows significant potential in treating mental disorders such as treatment-resistant depression (TRD), anxiety, obsessive–compulsive disorders (OCD), post-traumatic stress disorders (PTSD), and other conditions. [1]
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