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The final diagnosis of cervical cancer, including the stage of the cancer, is confirmed with additional testing. [ 12 ] Cancer staging is determined by where the tumor is located, the size of the tumor, and how much the tumor has spread beyond where it originally began, such as to nearby lymph nodes or different parts of the body.
Grading in cancer is distinguished from staging, which is a measure of the extent to which the cancer has spread. Pathology grading systems classify the microscopic cell appearance abnormality and deviations in their rate of growth with the goal of predicting developments at tissue level (see also the 4 major histological changes in dysplasia ).
The TNM Classification of Malignant Tumors (TNM) is a globally recognised standard for classifying the anatomical extent of the spread of malignant tumours (cancer). It has gained wide international acceptance for many solid tumor cancers, but is not applicable to leukaemia or tumors of the central nervous system .
The term "induction regimen" refers to a chemotherapy regimen used for the initial treatment of a disease. A " maintenance regimen " refers to the ongoing use of chemotherapy to reduce the chances of a cancer recurring or to prevent an existing cancer from continuing to grow.
The Eastern Cooperative Oncology Group (ECOG) began in 1955 as one of the first publicly funded cooperative groups to perform multi-center clinical trials for cancer research. [1] A cooperative group in oncology constitutes a large network of private and public medical institutions developing protocols for cancer treatments. Institutional ...
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