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There are efforts to define core sets of patient-relevant outcome variables to be measured in clinical trials in general [28] and for multi-modal pain therapy. [29] Meanwhile, a core outcome measure set based on PROMS was developed with routine data and validated for operationalizing success in multimodal pain therapy. [30]
The Patient-Reported Outcomes Measurement Information System [1] (PROMIS) provides clinicians and researchers access to reliable, valid, and flexible measures of health status that assess physical, mental, and social well–being from the patient perspective. PROMIS measures are standardized, allowing for assessment of many patient-reported ...
Outcome measurement is therefore an important but neglected tool in improving quality of healthcare provision. It has been argued that it is vital that the patient has been meaningfully involved in decisions about whether or not to embark on an intervention (e.g. a test, an operation, a medicine).
An outcome measure, endpoint, effect measure or measure of effect is a measure within medical practice or research, (primarily clinical trials) which is used to assess the effect, both positive and negative, of an intervention or treatment. [1] [2] Measures can often be quantified using effect sizes. [3]
Core outcome sets are commonly used by clinical investigators who conduct clinical trials for the treatment of a health condition. [2] [3] [4] The patient population associated with a particular core outcome set may vary, as some apply to all patients with that health condition and others apply to a small subset of that population. [2]
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Outcome measurement is a systematic way to assess the extent to which a program has achieved its intended outcomes. [18] According to Mouton (2009) measuring the impact of a program means demonstrating or estimating the accumulated differentiated proximate and emergent effect, some of which might be unintended and therefore unforeseen.
The selection of the appropriate effect measure should be based on clinical judgment in the context of the intervention being considered. A special case of CEA is cost–utility analysis, where the effects are measured in terms of years of full health lived, using a measure such as quality-adjusted life years (QALY) or disability-adjusted life ...