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A mouse model study on the role of protein kinase C gamma in pain sensitization found that mice lacking the protein also lacked the neuropathic pain sensitization seen in normal animals. [ 13 ] Thus, trauma victims (or patients in pain) are given painkillers (such as morphine ) as soon as possible to prevent pain sensitization .
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There are a wide variety of symptoms that have been found to be associated with sensory overload. These symptoms can occur in both children and adults. Some of these symptoms are: Irritability "Shutting down," or refusing to participate in activities and interact with others; Over-sensitivity to touch, movement, sights, or sounds
Research pre-dating the Arons' coining of the term "high sensitivity" includes that of German medicine professor Wolfgang Klages, who argued in the 1970s that the phenomenon of sensitive and highly sensitive humans is "biologically anchored" and that the "stimulus threshold of the thalamus" is much lower in these persons. [21]
Sensation seeking: high threshold and active response. Those who actively seek out a rich sensory filled environment. [86] Low neurological threshold; Sensitivity to stimuli: low threshold with passive response. Individuals who become distracted and uncomfortable when exposed to sensation but do not actively limit or avoid exposure to the ...
Hyperacusis is an increased sensitivity to sound and a low tolerance for environmental noise. Definitions of hyperacusis can vary significantly; it often revolves around damage to or dysfunction of the stapes bone, stapedius muscle or tensor tympani ().
The 'worst-case' sensitivity or specificity must be calculated in order to avoid reliance on experiments with few results. For example, a particular test may easily show 100% sensitivity if tested against the gold standard four times, but a single additional test against the gold standard that gave a poor result would imply a sensitivity of ...
Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [4] [5] [2] Symptoms in mild cases include high blood pressure and a fast heart rate; usually without a fever. [2]