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4843 18126 Ensembl ENSG00000007171 ENSMUSG00000020826 UniProt P35228 P29477 RefSeq (mRNA) NM_000625 NM_153292 NM_010927 NM_001313921 NM_001313922 RefSeq (protein) NP_000616 NP_001300850 NP_001300851 NP_035057 Location (UCSC) Chr 17: 27.76 – 27.8 Mb Chr 11: 78.81 – 78.85 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Nitric oxide synthase, inducible is an enzyme which is encoded ...
Enzyme induction is a process in which a molecule (e.g. a drug) induces (i.e. initiates or enhances) the expression of an enzyme. Enzyme inhibition can refer to the inhibition of the expression of the enzyme by another molecule; interference at the enzyme-level, basically with how the enzyme works.
Cloning of NOS enzymes indicates that cNOS include both brain constitutive and endothelial constitutive ; the third is the inducible gene. [10] Recently, NOS activity has been demonstrated in several bacterial species, including the notorious pathogens Bacillus anthracis and Staphylococcus aureus.
Regulation of gene expression, or gene regulation, [1] includes a wide range of mechanisms that are used by cells to increase or decrease the production of specific gene products (protein or RNA). Sophisticated programs of gene expression are widely observed in biology, for example to trigger developmental pathways, respond to environmental ...
Cytokine-inducible SH2-containing protein is a protein that in humans is encoded by the CISH gene. [ 5 ] [ 6 ] [ 7 ] CISH orthologs [ 8 ] have been identified in most mammals with sequenced genomes. CISH controls T cell receptor (TCR) signaling, and variations of CISH with certain SNPs are associated with susceptibility to bacteremia ...
54206 74155 Ensembl ENSG00000116285 ENSMUSG00000028967 UniProt Q9UJM3 Q99JZ7 RefSeq (mRNA) NM_018948 NM_133753 NM_001356323 RefSeq (protein) NP_061821 NP_598514 NP_001343252 Location (UCSC) Chr 1: 8 – 8.03 Mb Chr 4: 150.94 – 150.95 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse ERBB receptor feedback inhibitor 1 is a protein that in humans is encoded by the ERRFI1 gene. MIG6 is ...
Activin also regulates the morphogenesis of branching organs such as the prostate, lung, and especially kidney. Activin A increased the expression level of type-I collagen suggesting that activin A acts as a potent activator of fibroblasts. Lack of activin during development results in neural developmental defects.
Protein inhibitor of activated STAT (PIAS), also known as E3 SUMO-protein ligase PIAS, is a protein that regulates transcription in mammals. PIAS proteins act as transcriptional co-regulators with at least 60 different proteins in order to either activate or repress transcription .