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The name dorsal-column medial lemniscus comes from the two structures that carry the sensory information: the dorsal columns of the spinal cord, and the medial lemniscus in the brainstem. There are three groupings of neurons that are involved in the pathway: first-order neurons , second-order neurons , and third-order neurons .
Both dorsal column nuclei contain synapses from afferent nerve fibers that have travelled in the spinal cord. [2] They then send on second-order neurons of the dorsal column–medial lemniscal pathway. Neurons of the dorsal column nuclei eventually reach the midbrain and the thalamus. [3] They send axons that form the internal arcuate fibers ...
The dorsal column nuclei are responsible for fine touch, vibration, proprioception and two-point discrimination. The fibers of this decussation are called the internal arcuate fibers and are found at the superior aspect of the closed medulla oblongata, superior to the motor decussation. Neurons of these nuclei are second-order neurons in the ...
The ventral trigeminal tract - consists of second-order axons from the spinal trigeminal nucleus. These fibers cross the midline and ascend to the contralateral thalamus. The dorsal trigeminal tract - consists of second-order axons from the principal sensory nucleus of trigeminal nerve. These fibers do not cross the midline, and ascend to the ...
Glutamate and acetylcholine pathways from mesopontine ... Dorsal column–medial lemniscus pathway. Gracile fasciculus; ... Central gray and dorsal and ventral nuclei ...
The cutaneous receptors of the skin project in an orderly fashion to the spinal cord, and from there, via different afferent pathways (dorsal column-medial lemniscus tract and spinothalamic tract), to the ventral posterior nucleus of the thalamus and the primary somatosensory cortex. Again, adjacent areas on the skin are represented by adjacent ...
The posterior thoracic nucleus is a major relay center for unconscious proprioception. Sensory information from muscle spindles and tendon organs is carried by axons of larger neurons in dorsal root ganglia, which synapse onto neurons in the spinal cord including the posterior thoracic nucleus.
These axons enter the spinal column and penetrate the grey matter of the dorsal horn, where they synapse on second-order neurons in either the substantia gelatinosa of Rolando or the nucleus proprius. Those neurons project their axon to the anterolateral quadrant of the contralateral half of the spinal cord, where they give the spinothalamic tract