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This change reflects damage to vascular endothelium and increases the risk of long-term heart disease and an acute event such as a myocardial infarction (heart attack). Vaping is accompanied by a shift in balance of the autonomic (reflex) nervous system toward sympathetic predominance, which is also associated with increased cardiac risk.
Vaping-associated pulmonary injury (VAPI), [4] also known as vaping-associated lung injury (VALI) [1] or e-cigarette, or vaping, product use associated lung injury (E/VALI), [2] [a] is an umbrella term, [15] [16] used to describe lung diseases associated with the use of vaping products that can be severe and life-threatening. [3]
Smoking most commonly leads to diseases affecting the heart and lungs and will commonly affect areas such as hands or feet. First signs of smoking-related health issues often show up as numbness in the extremities, with smoking being a major risk factor for heart attacks, chronic obstructive pulmonary disease (COPD), emphysema, and cancer, particularly lung cancer, cancers of the larynx and ...
Cardiotoxicity is the occurrence of heart dysfunction as electric or muscle damage, resulting in heart toxicity. [1] This can cause heart failure, arrhythmia, myocarditis, and cardiomyopathy in patients. [2] Some effects are reversible, while in others, permanent damage requiring further treatment may arise. The heart becomes weaker and is not ...
A 2017 review states, "because nicotine targets the fetal brain, damage can be present, even when birth weight is normal." [ 90 ] A 2014 US Surgeon General report found "that nicotine adversely affects maternal and fetal health during pregnancy, and that exposure to nicotine during fetal development has lasting adverse consequences for brain ...
A 2020 review stated "Initial case reports of vaping-related lung injury date back to 2012, but the ongoing outbreak of EVALI began in the summer of 2019..." [11] At least 19 cases of vaping-associated pulmonary injuries had been reported worldwide prior to 2019. [12] Similar cases were reported in the UK and Japan before the outbreak. [13]
Today nicotine is less commonly used in agricultural insecticides, which was a main source of poisoning. More recent cases of poisoning typically appear to be in the form of Green Tobacco Sickness (GTS), [ 43 ] accidental ingestion of tobacco or tobacco products , or ingestion of nicotine-containing plants.
Metal parts of e-cigarettes in contact with the e-liquid can contaminate it with metals. [15] Heavy metals and metal nanoparticles have been found in tiny amounts in the e-cigarette aerosol. [notes 6] [15] Once aerosolized, the ingredients in the e-liquid go through chemical reactions that form new compounds not previously found in the liquid. [17]