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Vitamin D 3 (cholecalciferol) is produced industrially by exposing 7-dehydrocholesterol to UVB and UVC light, followed by purification. The 7-dehydrocholesterol is sourced as an extraction from lanolin, a waxy skin secretion in sheep's wool. [203] Vitamin D 2 (ergocalciferol) is produced in a similar way using ergosterol from yeast as a ...
The Institute of Medicine in 2010 recommended a maximum uptake of vitamin D of 4000 IU/d, finding that the dose for lowest observed adverse effect level is 40,000 IU daily for at least 12 weeks, [25] and that there was a single case of toxicity above 10 000 IU after more than seven years of daily intake; this case of toxicity occurred in ...
Day 2 of Amazon's 2024 October Prime Day sales event (formally called Prime Big Deal Days) is underway now, with brand new deals dropping throughout the day until the sale ends at midnight tonight ...
24,25-dihydroxyvitamin D 3 is formed from 25-hydroxyvitamin D 3 by the action of CYP24A1 (25-hydroxyvitamin D3-24-hydroxylase). CYP24A1 appears to be "a multicatalytic enzyme catalyzing most, if not all, of the reactions in the C-24/C-23 pathway of 25-OH-D 3 metabolism." [5]
Calcitriol is a hormone and the active form of vitamin D, normally made in the kidney. [8] [9] [10] It is also known as 1,25-dihydroxycholecalciferol.It binds to and activates the vitamin D receptor in the nucleus of the cell, which then increases the expression of many genes. [11]
896 12445 Ensembl ENSG00000112576 ENSMUSG00000034165 UniProt P30281 P30282 RefSeq (mRNA) NM_001136017 NM_001136125 NM_001136126 NM_001287427 NM_001287434 NM_001760 NM_001081635 NM_001081636 NM_007632 RefSeq (protein) NP_001129489 NP_001129597 NP_001129598 NP_001274356 NP_001274363 NP_001751 NP_001075104 NP_001075105 NP_031658 Location (UCSC) Chr 6: 41.93 – 42.05 Mb Chr 17: 47.82 – 47.91 Mb ...