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asthma Apolizumab [21] mab: humanized: HLA-DR: hematological cancers: Aprutumab ixadotin [22] mab: human: FGFR2: Arcitumomab [23] CEA-Scan: Fab' mouse: Carcinoembryonic antigen (CEA) gastrointestinal cancers (diagnosis) Ascrinvacumab [12] mab: human: activin receptor-like kinase 1: cancer Aselizumab [24] mab: humanized: L-selectin (CD62L ...
3578 16198 Ensembl ENSG00000145839 ENSMUSG00000021538 UniProt P15248 P15247 RefSeq (mRNA) NM_000590 NM_008373 RefSeq (protein) NP_000581 NP_032399 Location (UCSC) Chr 5: 135.89 – 135.9 Mb Chr 13: 56.63 – 56.63 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Interleukin 9, also known as IL-9, is a pleiotropic cytokine (cell signalling molecule) belonging to the group of ...
Interleukin 9 (IL-9) [30] is a cytokine that supports IL-2 independent and IL-4 independent growth of helper T cells. Early studies had indicated that Interleukin 9 and 7 seem to be evolutionary related [ 31 ] and Pfam, InterPro and PROSITE entries exist for interleukin 7/interleukin 9 family.
An anti-asthmatic agent, also known as an anti-asthma drug, refers to a drug that can aid in airway smooth muscle dilation to allow normal breathing during an asthma attack or reduce inflammation on the airway to decrease airway resistance for asthmatic patients, or both. The goal of asthmatic agents is to reduce asthma exacerbation frequencies ...
Omalizumab, sold under the brand name Xolair among others, is an injectable medication to treat severe persistent allergic forms of asthma, nasal polyps, urticaria (hives), [10] [11] and immunoglobulin E-mediated food allergy.
Dupilumab, sold under the brand name Dupixent, is a monoclonal antibody blocking interleukin 4 and interleukin 13 receptor signalling (IL-4R, IL-13R), used for allergic diseases such as atopic dermatitis (eczema), asthma and nasal polyps which result in chronic sinusitis.
Pitrakinra (trade name Aerovant) is a 15-kDa human recombinant protein of wild-type human interleukin-4 (IL-4). It is an IL-4 and IL-13 antagonist that has been studied in a phase IIb clinical trial for the treatment of asthma. Two point mutations on pitrakinra (position 121 mutated from arginine to aspartic acid and position 124 mutated from ...
Interleukin 9 receptor (IL9R) also known as CD129 (Cluster of Differentiation 129) is a type I cytokine receptor. IL9R also denotes its human gene. [5] The protein encoded by this gene is a cytokine receptor that specifically mediates the biological effects of interleukin 9 (IL9). The functional IL9 receptor complex requires this protein as ...
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