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Esterified estrogens (EEs), sold under the brand names Estratab and Menest among others, is an estrogen medication which is used hormone therapy for menopausal symptoms and low sex hormone levels in women, to treat breast cancer in both women and men, and to treat prostate cancer in men.
Estrogen conjugates are conjugated at the C3, C16α, and/or C17β positions, where hydroxyl groups are available. [1]Estrogen conjugates have been used as pharmaceutical estrogens, as in estrone sulfate as estropipate (piperazine estrone sulfate) and in conjugated estrogens (Premarin) and conjugated estriol (Progynon, Emmenin).
Conjugated estrogens (Premarin) – 25 mg/vial Estradiol cypionate (Depo-Estradiol, Estradiol Cypionate) – 5 mg/mL (1 mg/mL and 3 mg/mL discontinued) Estradiol valerate (Delestrogen, Estradiol Valerate) – 10 mg/mL, 20 mg/mL, 40 mg/mL
Conjugated estrogens (CEs), or conjugated equine estrogens (CEEs), sold under the brand name Premarin among others, is an estrogen medication which is used in menopausal hormone therapy and for various other indications. [11] [7] [1] [12] It is a mixture of the sodium salts of estrogen conjugates found in horses, such as estrone sulfate and ...
Estradiol sulfate (a minor constituent of conjugated estrogens (Premarin)) The following nitrogen mustard ester of estradiol is a cytostatic antineoplastic agent and has been marketed: [1] [2] Estramustine phosphate (Emcyt, Estracyt; estradiol 3-normustine 17β-phosphate)
An estrogen ester is an ester of an estrogen, most typically of estradiol but also of other estrogens such as estrone, estriol, and even nonsteroidal estrogens like diethylstilbestrol. [ 1 ] [ 2 ] [ 3 ] Esterification renders estradiol into a prodrug of estradiol with increased resistance to first-pass metabolism , slightly improving its oral ...
Those taking conjugated equine estrogens plus medroxyprogesterone acetate saw a 7% increase in HDL-C measures. So-called bad cholesterol — low-density lipoprotein cholesterol (LDL-C ...
Estrogen is associated with edema, including facial and abdominal swelling. Melanin. Estrogen is known to cause darkening of skin, especially in the face and areolae. [38] Pale skinned women will develop browner and yellower skin during pregnancy, as a result of the increase of estrogen, known as the "mask of pregnancy". [39]