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Three isoforms, FS-288, FS-300, and FS-315 have been reported. Two, FS-288 and FS-315, are created by alternative splicing of the primary mRNA transcript. FS-300 (porcine follistatin) is thought to be the product of posttranslational modification via truncation of the C-terminal domain from the primary amino-acid chain.
Follicle-stimulating hormone (FSH) is a gonadotropin, a glycoprotein polypeptide hormone. [1] FSH is synthesized and secreted by the gonadotropic cells of the anterior pituitary gland [2] and regulates the development, growth, pubertal maturation, and reproductive processes of the body.
Activin and inhibin are two closely related protein complexes that have almost directly opposite biological effects. Identified in 1986, [1] [2] activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle.
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2492 14309 Ensembl ENSG00000170820 ENSMUSG00000032937 UniProt P23945 P35378 RefSeq (mRNA) NM_000145 NM_181446 NM_013523 RefSeq (protein) NP_000136 NP_852111 NP_038551 Location (UCSC) Chr 2: 48.96 – 49.15 Mb Chr 17: 89.29 – 89.51 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse The follicle-stimulating hormone receptor or FSH receptor (FSHR) is a transmembrane receptor that ...
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Follitropin subunit beta also known as follicle-stimulating hormone beta subunit (FSH-B) is a protein that in humans is encoded by the FSHB gene. [ 5 ] [ 6 ] [ 7 ] Alternative splicing results in two transcript variants encoding the same protein.
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