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Testosterone cypionate is a testosterone ester and a long-lasting prodrug of testosterone in the body. [7] [2] [3] Because of this, it is considered to be a natural and bioidentical form of testosterone. [14] Testosterone cypionate was introduced for medical use in 1951.
High levels of testosterone are also achieved with a 60 mg dose of oral testosterone in men with liver cirrhosis. [2] These findings are attributed to induction of liver enzymes by testosterone and consequent activation of its own metabolism. [2] [27] Substitution dosages of oral testosterone in men are in the range of 400 to 800 mg/day.
Androgen replacement therapy (ART), often referred to as testosterone replacement therapy (TRT), is a form of hormone therapy in which androgens, often testosterone, are supplemented or replaced. It typically involves the administration of testosterone through injections, skin creams, patches, gels, pills, or subcutaneous pellets.
Some side effects may be ameliorated by using a shorter dosing interval (weekly or every ten days instead of twice monthly with testosterone enanthate or testosterone cypionate). 100 mg weekly gives a much lower peak level of testosterone than does 200 mg every two weeks, while still maintaining the same total dose of androgen.
Testosterone cypionate and testosterone enanthate were formerly available in combination with estradiol cypionate and estradiol valerate, respectively, under the brand names Depo-Testadiol and Ditate-DS, respectively, as oil solutions for intramuscular injection, but these formulations have been discontinued. [57]
The four testosterone esters are as follows; 30 mg testosterone propionate [1] 60 mg testosterone phenylpropionate [1] 60 mg testosterone isocaproate [1] 100 mg testosterone decanoate [1] Cumulatively, a 1 ml of the oil solution contains exactly 250 mg of above mentioned testosterone esters.
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