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  2. Post-exposure prophylaxis - Wikipedia

    en.wikipedia.org/wiki/Post-exposure_prophylaxis

    The CDC recommends PEP for any HIV-negative person who has recently been exposed to HIV for any reason. [25] To be most effective, treatment should begin within an hour of exposure. [26] After 72 hours PEP is much less effective, and may not be effective at all. [25] Prophylactic treatment for HIV typically lasts four weeks. [25] [27]

  3. Management of HIV/AIDS - Wikipedia

    en.wikipedia.org/wiki/Management_of_HIV/AIDS

    The combination of Rekambys and Vocabria injection is intended for maintenance treatment of adults who have undetectable HIV levels in the blood (viral load less than 50 copies/ml) with their current ARV treatment, and when the virus has not developed resistance to certain class of anti-HIV medicines called non-nucleoside reverse transcriptase ...

  4. List of antiretroviral fixed-dose combinations - Wikipedia

    en.wikipedia.org/wiki/List_of_antiretroviral...

    Antiretroviral drugs are used to manage HIV/AIDS. Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden. Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.

  5. Emtricitabine/tenofovir - Wikipedia

    en.wikipedia.org/wiki/Emtricitabine/tenofovir

    In 2019, Gilead Sciences challenged the validity of patents granted to the United States after 2015 for using the drug combination for HIV PrEP and post-exposure prophylaxis (PEP). [41] [42] [43] In July 2024, The Biden administration appealed the jury finding that ruled in favor of Gilead Sciences verdict that the U.S. government's patents are ...

  6. Pre-exposure prophylaxis for HIV prevention - Wikipedia

    en.wikipedia.org/wiki/Pre-exposure_prophylaxis...

    Truvada was previously only approved by the U.S. Food and Drug Administration (FDA) to treat HIV in those already infected. In 2012, the FDA approved the drug for use as pre-exposure prophylaxis (PrEP), based on growing evidence that the drug was safe and effective at preventing HIV in populations at increased risk of infection. [41]

  7. Zidovudine - Wikipedia

    en.wikipedia.org/wiki/Zidovudine

    It works by inhibiting the enzyme reverse transcriptase that HIV uses to make DNA and therefore decreases replication of the virus. [6] Zidovudine was first described in 1964. [7] It was resynthesized from a public-domain formula by Burroughs Wellcome. [8] It was approved in the United States in 1987 and was the first treatment for HIV.

  8. Dolutegravir/lamivudine/tenofovir - Wikipedia

    en.wikipedia.org/wiki/Dolutegravir/lamivudine/...

    As of 2019, it is listed by the World Health Organization (WHO) as the first-line treatment for adults with HIV/AIDS, with tenofovir/lamivudine/efavirenz as an alternative. [2] It may be used in people with both HIV and tuberculosis , however if the person is on rifampicin a larger dose of dolutegravir is needed.

  9. Tenofovir disoproxil - Wikipedia

    en.wikipedia.org/wiki/Tenofovir_disoproxil

    This version of tenofovir is often referred to simply as "tenofovir". In this version of the drug, the two negative charges of the tenofovir phosphonic acid group are masked, thus enhancing oral absorption. Tenofovir disoproxil was approved in the U.S. in 2001, for the treatment of HIV, and in 2008, for the treatment of chronic hepatitis B. [29 ...

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