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Parathyroid carcinoma is a rare cancer resulting in parathyroid adenoma to carcinoma progression. [1] It forms in tissues of one or more of the parathyroid glands (four pea-sized glands in the neck that make parathyroid hormone (PTH). PTH helps the body maintain normal levels of serum calcium by promoting calcium reabsorption from bone.
A parathyroid adenoma is a benign tumor of the parathyroid gland. It generally causes hyperparathyroidism; there are very few reports of parathyroid adenomas that were not associated with hyperparathyroidism. [1] A human being usually has four parathyroid glands located on the posterior surface of the thyroid in the neck.
The oversecretion of PTH is due to a parathyroid adenoma, parathyroid hyperplasia, or rarely, a parathyroid carcinoma. This disease is often characterized by the quartet stones, bones, groans, and psychiatric overtones referring to the presence of kidney stones , hypercalcemia, constipation, and peptic ulcers , as well as depression , respectively.
Tertiary: parathyroid adenoma, multiple benign tumors, parathyroid cancer, parathyroid hyperplasia, growth of parathyroid tissue, secondary hyperparathyroidism: Diagnostic method: High blood calcium and high PTH levels: Treatment: Surgery, intravenous normal saline: Frequency ~2 per 1,000
Approximately 60 percent of parathyroid adenomas may be imaged by sestamibi scanning. The natural distribution of causation for primary hyperparathyroidism is roughly 85% solitary adenomas, 10-15% diffuse hyperplasia, and 1% cancer. Imaging is not as reliable in patients with multiglandular parathyroid disease.
A parathyroid neoplasm is a tumor of the parathyroid gland. Types include: Parathyroid adenoma [1] Parathyroid carcinoma [citation needed] References