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Amygdalohippocampectomy is a surgical procedure for the treatment of epilepsy.It consists of the removal of the hippocampus, which has a role in memory, spatial awareness, and navigation, [1] and the amygdalae, which have a role in the processing and memory of emotional reactions, [2] both structures forming part of the limbic system of the brain.
Additional epilepsy surgery following hemispherectomy is rare (4.5%), [7] but may be recommended if there is a residual connection between the two hemispheres that is causing frequent seizures. Mortality rates are low and estimated to be <1% to 2.2%.
Once the epilepsy focus is located, the specific surgery involved in treatment is decided on. The type of surgery depends on the location of the seizure focal point. Surgeries for epilepsy treatment include, but are not limited to: temporal lobe resection, hemispherectomy, ground temporal and extratemporal resection, parietal resection ...
The surgery is a palliative treatment method for many forms of epilepsy, including atonic seizures, generalized seizures, and Lennox-Gastaut syndrome. [5] In a 2011 study of children with intractable epilepsy accompanied by attention deficit disorder, EEG showed an improvement to both seizures and attention impairments following corpus ...
DBS is FDA approved or has FDA device exemptions for treatment of Parkinson's disease, dystonia, essential tremor, obsessive-compulsive disorder and epilepsy. In Europe, beyond these indications, a CE mark exists for treatment of Alzheimer's disease. There was a past device exemption for OCD as well but this has not been renewed. [37]
People with epilepsy are evaluated on a case-by-case basis in centres that are familiar with and have expertise in epilepsy surgery. [16] Results from a 2023 systematic review found that surgical interventions for children aged 1–36 months with drug-resistant epilepsy can lead to significant seizure reduction or freedom, especially when other ...