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Fluphenazine, sold under the brand name Prolixin among others, is a high-potency typical antipsychotic medication. [2] It is used in the treatment of chronic psychoses such as schizophrenia , [ 2 ] [ 3 ] and appears to be about equal in effectiveness to low-potency antipsychotics like chlorpromazine . [ 4 ]
“There are many medications that may cause weight gain,” says W. Scott Butsch, M.D., director of obesity medicine in the Bariatric and Metabolic Institute at the Cleveland Clinic.
However, many are associated with an infamous side effect: weight gain. Luckily, some antidepressants are less likely to cause weight gain than others. In fact, there are even some antidepressants ...
Many common antidepressants can cause weight gain over time, but that's not a reason to avoid taking medication for mental health issues, experts say. - Joe Raedle/Getty Images/File
Both generations of medication tend to block receptors in the brain's dopamine pathways, but atypicals at the time of marketing were claimed to differ from typical antipsychotics in that they are less likely to cause extrapyramidal symptoms (EPS), which include unsteady Parkinson's disease-type movements, internal restlessness, and other ...
The atypical antipsychotics (AAP), also known as second generation antipsychotics (SGAs) and serotonin–dopamine antagonists (SDAs), [1] [2] are a group of antipsychotic drugs (antipsychotic drugs in general are also known as tranquilizers and neuroleptics, although the latter is usually reserved for the typical antipsychotics) largely introduced after the 1970s and used to treat psychiatric ...
It has only low and likely clinically unimportant affinity for the serotonin 5-HT 2C receptor, which may underlie its low propensity for appetite stimulation and weight gain. [ 67 ] [ 75 ] [ 76 ] The drug also has negligible affinity for the histamine H 1 receptor and the muscarinic acetylcholine receptors , and hence has no antihistamine or ...
Prozac was not associated with a six-month weight change, while Wellbutrin users were 15% less likely to experience a 5% weight gain. Wellbutrin continued to be associated with the least weight ...