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Doxylamine succinate is the active ingredient in many over-the-counter sleep-aids branded under various names. Doxylamine succinate and pyridoxine (Vitamin B6) are the ingredients of Diclegis, approved by the FDA in April 2013 becoming the only drug approved for morning sickness [46] with a class A safety rating for pregnancy (no evidence of risk).
Melatonin, an indoleamine, is a natural compound produced by various organisms, including bacteria and eukaryotes. [1] Its discovery in 1958 by Aaron B. Lerner and colleagues stemmed from the isolation of a substance from the pineal gland of cows that could induce skin lightening in common frogs.
Melatonin as a medication and supplement. Melatonin is a naturally occurring hormone produced in the brain that is also used as a dietary supplement and medication. [9][12] As a hormone, melatonin is released by the pineal gland and is involved in sleep–wake cycles. [9][12] As a supplement, it is often used for the attempted short-term ...
3,564,345 United States dollar (2017, 2018) The National Sleep Foundation (NSF) is an American non-profit, charitable organization. Founded in 1990, its stated goal is to provide expert information on health-related issues concerning sleep. [1] It is largely funded by pharmaceutical and medical device companies.
For people with insomnia who spend a significant amount of their time in bed awake, feeling anxious and irritated, sleep restriction therapy can help boost their sleep efficiency, making the bed a ...
Diphenhydramine is a potent anticholinergic agent and potential deliriant in higher doses. This activity is responsible for the side effects of dry mouth and throat, increased heart rate, pupil dilation, urinary retention, constipation, and, at high doses, hallucinations or delirium.
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