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Hairy leukoplakia is a white patch on the side of the tongue with a corrugated or hairy appearance. It is caused by Epstein-Barr virus (EBV) and occurs usually in persons who are immunocompromised , especially those with human immunodeficiency virus infection/ acquired immunodeficiency syndrome (HIV/AIDS).
Oral hairy leukoplakia is a corrugated ("hairy") white lesion on the sides of the tongue caused by opportunistic infection with Epstein-Barr virus on a systemic background of immunodeficiency, almost always human immunodeficiency virus (HIV) infection. [15]
The tongue is only one of the 10 ways you can see disease written all over your face. There are a whole host of other reasons for bumps on the tongue. Bumps on the tongue come in many other varieties.
Oral hairy leukoplakia (seen in people with immunosuppression, caused by Epstein–Barr virus) Oral candidiasis can affect the tongue. Risk factors for oral candidiasis include antibiotic and corticosteroid use, and immunodeficiency (e.g. HIV ), [ 5 ] or diabetes mellitus ).
a. Early lesions, blanching of the oral mucosa; b. Older lesions, vertical and circular palpable fibrous bands in and around the mouth or lips, resulting in a mottled, marble-like appearance of the buccal mucosa; Stage 3: Sequelae of oral submucous fibrosis a. Leukoplakia; b. Speech and hearing deficits
Hairy tongue may be confused with hairy leukoplakia, however the latter usually occurs on the sides of the tongue and is associated with an opportunistic infection with Epstein–Barr virus on a background immunocompromise (almost always human immunodeficiency virus infection but rarely other conditions which suppress the immune system). [6]
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Early lesions may appear as thin, translucent and granular or wrinkled mucosa. [2] [6] The later lesion may appear thicker, more opaquely white and hyperkeratotic with fissures and folds. [6] [2] Oral snuff causes more pronounced changes in the oral mucosa than tobacco chewing. [1] Snuff dipping is associated more with verrucous keratosis. [1]