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Moxidectin is an anthelmintic drug used in animals to prevent or control parasitic worms , such as heartworm and intestinal worms, in dogs, cats, horses, cattle, sheep and wombats. [4] Moxidectin kills some of the most common internal and external parasites by selectively binding to a parasite's glutamate-gated chloride ion channels .
Equine Wormer Drugs; Chemical class Specific chemical sample brand names Benzimidazole Fenbendazole: Panacur, Safe-Guard Mebendazole: Equivurm, Telmin Oxibendazole: Anthelcide EQ Pyrantels Pyrantel pamoate: Strongid P, Strongid T, Rotectin 2 Pyrantel tartrate (daily wormer) Strongid C, Equi-Aid CW, Pellet-Care P Macrocyclic Lactones Ivermectin
Oxibendazole is a benzimidazole drug that is used to protect against roundworms, strongyles, threadworms, pinworms and lungworm infestations in horses and some domestic pets. [ 1 ] [ 2 ] It is usually white to yellowish in appearance, and may take the form of a powder, tablet or paste.
flunixin meglumine – nonsteroidal anti-inflammatory drug used as an analgesic and antipyretic in horses; fluralaner - antiparasitic; frunevetmab - nerve growth factor inhibitor monoclonal antibody used for osteoarthritis in cats; furosemide – diuretic used to prevent exercise-induced pulmonary hemorrhage in horses
Ivermectin is an antiparasitic drug. [7] After its discovery in 1975, [8] its first uses were in veterinary medicine to prevent and treat heartworm and acariasis. [9] Approved for human use in 1987, [10] it is used to treat infestations including head lice, scabies, river blindness (onchocerciasis), strongyloidiasis, trichuriasis, ascariasis and lymphatic filariasis.
The ways in which anthelmintics are used have contributed to a major anthelmintic resistance issue worldwide. From the 1950s to the 1980s, new classes of effective and inexpensive anthelmintics were made available every decade, leading to excessive use throughout agriculture and disincentivizing alternative anti-nematodal strategies. [13]