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Pyrantel is a medication used to treat a number of parasitic worm infections. [2] This includes ascariasis , hookworm infections , enterobiasis (pinworm infection), trichostrongyliasis , and trichinellosis . [ 2 ]
Fenbendazole is a broad spectrum benzimidazole anthelmintic used against gastrointestinal parasites including: giardia, roundworms, hookworms, whipworms, the tapeworm genus Taenia (but not effective against Dipylidium caninum, a common dog tapeworm), pinworms, aelurostrongylus, paragonimiasis, strongyles, and strongyloides that can be administered to sheep, cattle, horses, fish, dogs, cats ...
Pyrantel pamoate (also called pyrantel embonate, brand names e.g., Reese's Pinworm Medicine, Pin-X, Combantrin, Anthel, Helmintox, and Helmex) kills adult pinworms through neuromuscular blockade, [27] and is considered as effective as the benzimidazole compounds and is used as a second-line medication. [9]
Praziquantel has a serum half-life of 0.8 to 1.5 hours in adults with normal renal and liver function. Metabolites have a half-life of 4 to 5 hours. In patients with significantly impaired liver function ( Child-Pugh score B and C), the serum half-life is increased to 3 to 8 hours.
In humans, treatment is by anthelminthic medications, such as albendazole and mebendazole. [13] Treatment in animals can be done with a variety of anthelminthics. [1] A high-protein diet, supplemental iron, or a blood transfusion may also be necessary. [1] Levamisole and pyrantel pamoate are also used to treat hookworm anemia and hookworm disease.
Those recommended by the World Health Organization for ascariasis are: albendazole, mebendazole, levamisole and pyrantel pamoate. [2] Single-dose of albendazole, mebendazole, and ivermectin are effective against ascariasis. They are effective at removing parasites and eggs from the intestines. [35]