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The third trimester is defined as starting, between the beginning of week 28 (27 weeks + 0 days of GA) [37] or beginning of week 29 (28 weeks + 0 days of GA). [4] It lasts until childbirth . Timeline of pregnancy, including (from top to bottom): Trimesters, embryo/fetus development, gestational age in weeks and months, viability and maturity stages
Signs and symptoms of pregnancy typically change as pregnancy progresses, although several symptoms may be present throughout. Depending on severity, common symptoms in pregnancy can develop into complications. [1] Pregnancy symptoms may be categorized based on trimester as well as region of the body affected.
Most women with this condition present in the third trimester (although it can present as early as seven weeks) with itching without a rash. Typically, the itching is localized to the palms of the hands and soles of the feet, but can be anywhere on the body. Hallmarks of ICP include the following symptoms: [5] Most common:
More concerning symptoms that may require assessment by a healthcare professional include: [1] Any bleeding or fluid leakage from the vagina; Contractions that are strong, frequent (every 5 minutes), and persisting for an hour; Changes or significant decreases in fetal movement
In 70% of cases before childbirth, the condition manifests in the third trimester, but 10% and 20% of the cases exhibit symptoms before and after the third trimester, respectively. Postpartum occurrences are also observed in 30% of all HELLP syndrome cases. [51]
Initial sway, total sway, and sway velocity (see figure for description of variables) are significantly less during the third trimester than during the second trimester and when compared to non-pregnant women. These biomechanical characteristics are possible reasons why falls are more prevalent during the second trimester during pregnancy.