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  2. Penicillin - Wikipedia

    en.wikipedia.org/wiki/Penicillin

    6-Aminopenicillanic acid (6-APA) is a compound derived from penicillin G. 6-APA contains the beta-lactam core of penicillin G, but with the side chains stripped off; 6-APA is a useful precursor for manufacturing other penicillins. There are many semi-synthetic penicillins derived from 6-APA and these are in three groups: antistaphylococcal ...

  3. 6-APA - Wikipedia

    en.wikipedia.org/wiki/6-APA

    6-APA ((+)-6-aminopenicillanic acid) is a chemical compound used as an intermediate in the synthesis of β–lactam antibiotics. The major commercial source of 6-APA is still natural penicillin G. The semi-synthetic penicillins derived from 6-APA are also referred to as penicillins and are considered part of the penicillin family of antibiotics ...

  4. β-Lactam antibiotic - Wikipedia

    en.wikipedia.org/wiki/Β-Lactam_antibiotic

    β-Lactam antibiotics are indicated for the prevention and treatment of bacterial infections caused by susceptible organisms. At first, β-lactam antibiotics were mainly active only against gram-positive bacteria, yet the recent development of broad-spectrum β-lactam antibiotics active against various gram-negative organisms has increased their usefulness.

  5. Production of antibiotics - Wikipedia

    en.wikipedia.org/wiki/Production_of_antibiotics

    Production of antibiotics is a naturally occurring event, that thanks to advances in science can now be replicated and improved upon in laboratory settings. Due to the discovery of penicillin by Alexander Fleming, and the efforts of Florey and Chain in 1938, large-scale, pharmaceutical production of antibiotics has been made possible.

  6. List of β-lactam antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_β-lactam_antibiotics

    This is a list of common β-lactam antibiotics—both administered drugs and those not in clinical use—organized by structural class. Antibiotics are listed alphabetically within their class or subclass by their nonproprietary name. If an antibiotic is a combination drug, both ingredients will be listed.

  7. List of antibiotics - Wikipedia

    en.wikipedia.org/wiki/List_of_antibiotics

    The following is a list of antibiotics. The highest division between antibiotics is bactericidal and bacteriostatic. Bactericidals kill bacteria directly, whereas bacteriostatics prevent them from dividing. However, these classifications are based on laboratory behavior.

  8. History of penicillin - Wikipedia

    en.wikipedia.org/wiki/History_of_penicillin

    Two 23,000-litre (5,000 imp gal) tanks became operational in 1948, followed by eight more. During the 1950s and 1960s, CSL produced semisynthetic penicillin as well. Penicillin was also produced by F.H. Faulding in South Australia, Abbott Laboratories in New South Wales and Glaxo in Victoria. By the 1970s there was a worldwide glut of ...

  9. List of infectious diseases - Wikipedia

    en.wikipedia.org/wiki/List_of_infectious_diseases

    Penicillinase-resistant semisynthetic penicillin or a first-generation cephalosporin: No Trypanosoma cruzi: Chagas disease (American trypanosomiasis) Microscopic examination of fresh anticoagulated blood, or its buffy coat, for motile parasites; or by preparation of thin and thick blood smears stained with Giemsa.