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The sodium–potassium pump (sodium–potassium adenosine triphosphatase, also known as Na + /K +-ATPase, Na + /K + pump, or sodium–potassium ATPase) is an enzyme (an electrogenic transmembrane ATPase) found in the membrane of all animal cells. It performs several functions in cell physiology. The Na + /K +-ATPase enzyme is active (i.e. it ...
Active transport is essential for various physiological processes, such as nutrient uptake, hormone secretion, and nig impulse transmission. For example, the sodium-potassium pump uses ATP to pump sodium ions out of the cell and potassium ions into the cell, maintaining a concentration gradient essential for cellular function. Active transport ...
11928 Ensembl ENSG00000163399 ENSMUSG00000033161 UniProt P05023 Q5TC02 Q8VDN2 RefSeq (mRNA) NM_000701 NM_001001586 NM_001160233 NM_001160234 NM_144900 RefSeq (protein) NP_000692 NP_001153705 NP_001153706 NP_659149 Location (UCSC) Chr 1: 116.37 – 116.41 Mb Chr 3: 101.48 – 101.51 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Protein domain Gastric H + /K + -ATPase, N terminal ...
Diffusion vs. Transport. In biology, an ion transporter is a transmembrane protein that moves ions (or other small molecules) across a biological membrane to accomplish many different biological functions, including cellular communication, maintaining homeostasis, energy production, etc. [1] There are different types of transporters including pumps, uniporters, antiporters, and symporters.
The sodium–potassium pump, a critical enzyme for regulating sodium and potassium levels in cells. Sodium ions (Na +) are necessary in small amounts for some types of plants, [1] but sodium as a nutrient is more generally needed in larger amounts [1] by animals, due to their use of it for generation of nerve impulses and for maintenance of electrolyte balance and fluid balance.
The sodium–potassium pump is a critical enzyme for regulating sodium and potassium levels in cells. Potassium is the main intracellular ion for all types of cells, while having a major role in maintenance of fluid and electrolyte balance. [1] [2] Potassium is necessary for the function of all living cells and is thus present in all plant and ...
The major functions of enterocytes include: [1] Ion uptake, including sodium, calcium, magnesium, iron, zinc, and copper. This typically occurs through active transport. Water uptake. This follows the osmotic gradient established by Na+/K+ ATPase on the basolateral surface. This can occur transcellularly or paracellularly.
The SGLT functions to couple the transport of sodium in the exoplasmic space down its concentration gradient (again, established by the active transport of sodium out of the cell by the sodium-potassium pump) into the cytoplasmic space to the transport of glucose in the exoplasmic space against its concentration gradient into the cytoplasmic ...