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Concentric myometrial hyperplasia frequent around adenomyotic foci; Variants: Gland-poor, stroma-poor, intravascular [23] Differential Diagnosis: Adenomyoma; Myo-invasive endometrial endometrioid carcinoma (vs. stroma-poor adenomyosis) Low-grade endometrial stromal sarcoma (vs. gland-poor and intravascular adenomyosis) [23]
In the event no embryo is implanted, the decidualized endometrial lining is shed or, as is the case with species that follow the estrous cycle, absorbed. [1] In menstruating species , decidualization is spontaneous and occurs as a result of maternal hormones.
Cancer is a disorder of cell life cycle alteration that leads (non-trivially) to excessive cell proliferation rates, typically longer cell lifespans and poor differentiation. The grade score (numerical: G1 up to G4) increases with the lack of cellular differentiation - it reflects how much the tumor cells differ from the cells of the normal ...
Uterine adenomyoma, the localized form of uterine adenomyosis, is a tumor composed of endometrial gland tissue and smooth muscle in the myometrium. [2] Adenomyomas containing endometrial glands are also found outside of the uterus, most commonly on the uterine adnexa but can also develop at distant sites outside of the pelvis . [ 3 ]
ITCs for endometrial cancers are defined as less than or equal to 0.2 mm or single cells or clusters of cells less than or equal to 200 cells in a single lymph node cross section. [68] Myometrial invasion and involvement of the pelvic and para-aortic lymph nodes are the most commonly seen patterns of spread. [2]
Asherman's syndrome, also known as intrauterine adhesions, occurs when the basal layer of the endometrium is damaged by instrumentation (e.g., D&C) or infection (e.g., endometrial tuberculosis) resulting in endometrial sclerosis and adhesion formation partially or completely obliterating the uterine cavity.
The myometrium is located between the endometrium (the inner layer of the uterine wall) and the serosa or perimetrium (the outer uterine layer).. The inner one-third of the myometrium (termed the junctional or sub-endometrial layer) appears to be derived from the Müllerian duct, while the outer, more predominant layer of the myometrium appears to originate from non-Müllerian tissue and is ...
These are enlarged endometrial stromal cells, which resemble epithelium (and are referred to as "epithelioid"). Decidualization includes the process of differentiation of the spindle-shape stromal fibroblasts into the plump secretory decidual cells, which create a pericellular extracellular matrix rich in fibronectin and laminin (similar to ...