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Cannabinoids (/ k ə ˈ n æ b ə n ɔɪ d z ˌ ˈ k æ n ə b ə n ɔɪ d z /) are compounds found in the cannabis plant or synthetic compounds that can interact with the endocannabinoid system. [1] [2] The most notable cannabinoid is the phytocannabinoid tetrahydrocannabinol (THC) (Delta-9-THC), the primary intoxicating compound in cannabis.
There is a slight increase in dose proportionality in terms of peak and area-under-the-curve levels of THC with increasing oral doses over a range of 2.5 to 10 mg. [22] A high-fat meal delays time to peak concentrations of oral THC by 4 hours on average and increases area-under-the-curve exposure by 2.9-fold, but peak concentrations are not ...
[1] [2] THC and CBD are stored mostly in the trichomes of the plant, [3] and can cause psychological and physical impairment in the user, via the endocannabinoid system and unique receptors. [ 4 ] [ 5 ] THC increases dopamine levels in the brain, which attributes to the euphoric and relaxed feelings cannabis provides.
Kief (from Arabic كيف kīf, "Joy, pleasure" [1] [2]), sometimes transliterated as keef, also known as "Dust" and "Chief" a.k.a cannabis crystals among other names, refers to the pure and clean collection of loose cannabis trichomes, which are accumulated by being sifted from cannabis flowers or buds with a mesh screen or sieve.
Delta-1, Delta-6, and Delta 3,4-Tetrahydrocannabinol are alternative names for Delta-9, Delta-8, and Delta-6a10a Tetrahydrocannabinol, respectively. [ 73 ] A 2023 paper seeking the regulation of cannabinoid terminology coined the term "derived psychoactive cannabis products" to accurately and usefully distinguish said products whilst excluding ...
The Single Convention is the main international treaty related to Cannabis sativa L. and its products.In its Article 1, the Single Convention defines "cannabis" as the "flowering or fruiting tops of the cannabis plant (excluding the seeds and leaves when not accompanied by the tops) from which the resin has not been extracted, by whatever name they may be designated;" while "cannabis resin" is ...
Gaoni and Mechoulam [25] also described a method for converting CBD to Δ9-THC comprising refluxing a mixture of CBD in ethanol containing 0.05% hydrogen chloride for 2 hours. Percentage yield of Δ9-THC (Δ1-THC) was 2%. [26] [27] Using boron trifluoride, the yield was 70% [28] although purity was not given. [29]