Search results
Results From The WOW.Com Content Network
It was discovered in 2000 as one of two improved mutants by H. Bujard and his colleagues after random mutagenesis of the Tet repressor part of the transactivator gene. [6] Tet-On 3G (also known as rtTA-V10 [7]) is similar to Tet-On Advanced but was derived from rtTA2 S-S2 rather than rtTA2 S-M2. It is also human codon optimized and composed of ...
The transactivator gene expresses a transcription factor that binds to specific promoter region of DNA. By binding to the promoter region of a gene, the transcription factor causes that gene to be expressed. The expression of one transactivator gene can activate multiple genes, as long as they have the same, specific promoter region attached.
A user will input a number and the Calculator will use an algorithm to search for and calculate closed-form expressions or suitable functions that have roots near this number. Hence, the calculator is of great importance for those working in numerical areas of experimental mathematics. The ISC contains 54 million mathematical constants.
An inversion may be denoted by the pair of places (2, 4) or the pair of elements (5, 2). The inversions of this permutation using element-based notation are: (3, 1), (3, 2), (5, 1), (5, 2), and (5,4). In computer science and discrete mathematics, an inversion in a sequence is a pair of elements that are out of their natural order.
[2] [3] Binding of the activator-coactivator complex increases the speed of transcription by recruiting general transcription machinery to the promoter, therefore increasing gene expression. [ 3 ] [ 4 ] [ 5 ] The use of activators and coactivators allows for highly specific expression of certain genes depending on cell type and developmental stage.
Thus TET enzymes largely initiate demethylation at 5mCpG sites. Oxoguanine glycosylase (OGG1) is one example of a protein that recruits a TET enzyme. TET1 is able to act on 5mCpG if an ROS has first acted on the guanine to form 8-hydroxy-2'-deoxyguanosine (8-OHdG or its tautomer 8-oxo-dG), resulting in a 5mCp-8-OHdG dinucleotide (see Figure). [10]
17684 Ensembl ENSG00000164442 ENSMUSG00000039910 UniProt Q99967 O35740 RefSeq (mRNA) NM_006079 NM_001168388 NM_001168389 NM_010828 RefSeq (protein) NP_001161860 NP_001161861 NP_006070 NP_034958 Location (UCSC) Chr 6: 139.37 – 139.37 Mb Chr 10: 17.6 – 17.6 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cbp/p300-interacting transactivator 2 is a protein that in humans is encoded ...
Hybrid Reverse Monte Carlo (HRMC) [19] [20] is a code capable of fitting both the pair correlation function and structure factor along with bond angle and coordination distributions. Unique to this code is the implementation of a number of empirical interatomic potentials for carbon (EDIP), silicon (EDIP [ 21 ] and Stillinger-Weber [ 22 ] ) and ...