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Chandler's disease, also known as idiopathic avascular osteonecrosis of the femoral head (ANFH or ONFH), is a rare condition in which the bone cells in the head of the femur (FH) die due to lack of blood. This disease is caused when blood flow is reduced to the part of a bone near a joint.
Avascular necrosis (AVN), also called osteonecrosis or bone infarction, is death of bone tissue due to interruption of the blood supply. [1] Early on, there may be no symptoms. [ 1 ] Gradually joint pain may develop, which may limit the person's ability to move. [ 1 ]
In radiology, the crescent sign is a finding on conventional radiographs that is associated with avascular necrosis. [1] [2] [3] It usually occurs later in the disease, in stage III of the four-stage Ficat classification system. [1] It appears as a curved subchondral radiolucent line that is often found on the proximal femoral or humeral head. [1]
Dysbaric osteonecrosis or DON is a form of avascular necrosis where there is death of a portion of the bone that is thought to be caused by nitrogen (N 2) embolism (blockage of the blood vessels by a bubble of nitrogen coming out of solution) in divers. [1] Although the definitive pathologic process is poorly understood, there are several ...
On the AP view Klein’s line, tangent to the lateral aspect of the femoral neck, does not intersect the femoral head indicating that it is displaced. SCFE may compromise the blood supply to the femoral head and cause avascular necrosis, mainly when there is instability between the fragments. [1]
The pathology of avascular necrosis followed by revascularization and bony remodeling of the femoral head in the dog certainly suggests a vascular etiology, though the cause of the condition is not completely understood. [40] Hip pain is usually seen by the age of 6 to 8 months. [41] The disease is bilateral in 12–16% of cases. [42]
Spontaneous osteonecrosis of the knee is the result of vascular arterial insufficiency to the medial femoral condyle of the knee resulting in necrosis and destruction of bone. It is often unilateral and can be associated with a meniscal tear. [1]
In the cancellous portion of femoral head it is not uncommon to find trabeculae with apparently intact osteocytes which seem to be "alive" but are no longer synthesizing collagen. This appears to be consistent with the findings in alveolar cancellous bone. [25] Osteonecrosis can affect any bone, but the hips, knees and jaws are most often involved.