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Lymphedema is most frequently a complication of cancer treatment or parasitic infections, but it can also be seen in a number of genetic disorders. Tissues with lymphedema are at high risk of infection because the lymphatic system has been compromised. [3] Though incurable and progressive, a number of treatments may improve symptoms. [2]
The procedure is most effective in patients with early-stage lymphedema or when there is still a measurable amount of functional lymphatic flow. It is frequently used in combination with conservative treatments such as compression therapy, manual lymphatic drainage, and exercise regimes as part of comprehensive lymphedema management.
The SSRI medication sertraline is approved as an anti-depressant but is also commonly prescribed off-label to help men suffering from premature ejaculation. [16] Tramadol, an opioid painkiller, is used to treat premature ejaculation, [17] and may also be applied against restless legs syndrome. [citation needed]
Phlebetic lymphedema (or phlebolymphedema) is seen in untreated chronic venous insufficiency and is the most common type of edema (approx. 90%). [14] It is a combination venous/lymphatic disorder that originates in defective "leaky" veins that allows the blood to back flow ( venous reflux ), slowing the return of the blood to the heart ( venous ...
The pathophysiology is not yet well understood. Leukocytoclastic vasculitis is proposed to be the underlying cause resulting in reactive lymphedema. [2] Prolonged standing with full knee extension and minimal movement for a prolonged period of time is postulated to induce a temporary failure in pumping the venous and lymphatic systems in the calf region leading to acute gravity-dependent ...
Secondary lymphedema is a condition characterized by swelling of the soft tissues in which an excessive amount of lymph has accumulated, and is caused by certain malignant diseases such as Hodgkin's disease and Kaposi sarcoma. [1]: 849