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The remainder of the serum cholesterol after subtracting the HDL is the non-HDL cholesterol. The concentration of these other components, which may cause atheroma, is known as the non-HDL-C. This is now preferred to LDL-C as a secondary marker as it has been shown to be a better predictor and it is more easily calculated. [10]
Reference ranges (reference intervals) for blood tests are sets of values used by a health professional to interpret a set of medical test results from blood samples. Reference ranges for blood tests are studied within the field of clinical chemistry (also known as "clinical biochemistry", "chemical pathology" or "pure blood chemistry"), the ...
An ideal LDL range is below 100. If you already have heart disease, your doctor will likely prefer to see LDL levels below 70. And if you’re especially high risk, that level should be below 55.
All the lipoproteins carry cholesterol, but elevated levels of the lipoproteins other than HDL (termed non-HDL cholesterol), particularly LDL-cholesterol, are associated with an increased risk of atherosclerosis and coronary heart disease. [4] In contrast, higher HDL cholesterol levels are protective. [5]
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The chemical reaction is the same as the total cholesterol measurement, except that the enzymes are blocked from acting on non-HDL lipoproteins by the reagent and their own PEG tails. [8] From these three data LDL may be calculated. According to Friedewald's equation: [9] [LDL] = [Total cholesterol] − [HDL] − [Triglycerides] / 5