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Roth's spots, also known as Litten spots or the Litten sign, [1] are non-specific red lesions with white or pale centres, seen on the retina of the eye and although traditionally associated with infective endocarditis, can occur in a number of other conditions including hypertension, diabetes, collagen vascular disease, extreme hypoxia, leukemia and HIV.
Other signs of endocarditis include Roth's spots and Janeway lesions. The latter, which also occur on the palms and soles, can be differentiated from Osler's nodes because they are non-tender. [3] Osler's nodes can also be seen in Systemic lupus erythematosus; Marantic endocarditis; Disseminated gonococcal infection; Distal to infected arterial ...
Moritz Roth (25 December 1839, in Basel – 4 November 1914, in Gottlieben am Untersee) was a Swiss pathologist remembered for describing Roth's spots. He studied medicine at Würzburg , Göttingen , Berlin and Basel, where he received his doctorate in 1864.
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A major cause of Bitot's spots is vitamin A deficiency (VAD). [4] Rarely, pellagra due to deficiency of vitamin B 3 (niacin) may also cause Bitot's spots. [5] They can also be caused by Colestyramine , which is a bile acid sequestrant which can reduce the absorption of fat soluble vitamins (Vitamins A, D, E, K)
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Fuchs spots are caused by regression of choroidal neovascularization. [3] Since it is a medical sign, treatment is given for the actual cause. Photothermal laser ablation, photodynamic therapy, anti-VEGF therapy, or a combination of these are the treatment options of choroidal neovascularization due to pathological myopia. [3] [1]
UPDATE, 8/20/24 at 11:55 a.m. ET: TikTok star Kyle Marisa Roth’s cause of death has been revealed four months after her April death. Roth’s death was caused by a cardiac arrhythmia due to ...