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Virus latency (or viral latency) is the ability of a pathogenic virus to lie dormant within a cell, denoted as the lysogenic part of the viral life cycle. [1] A latent viral infection is a type of persistent viral infection which is distinguished from a chronic viral infection.
In epidemiology, particularly in the discussion of infectious disease dynamics (modeling), the latent period (also known as the latency period or the pre-infectious period) is the time interval between when an individual or host is infected by a pathogen and when that individual becomes infectious, i.e. capable of transmitting pathogens to ...
Incubation period (also known as the latent period or latency period) is the time elapsed between exposure to a pathogenic organism, a chemical, or radiation, and when symptoms and signs are first apparent. [1]
Human Immunodeficiency Virus (HIV) has the capability to enter a latent stage of infection where it exists as a dormant provirus in CD4+ T-cells.Most latently infected cells are resting memory T cells, [1] however a small fraction of latently infected cells isolated from HIV patients are naive CD4 T cells.
The herpes virus can then exit this dormant stage and re-enter the lytic cycle, causing disease symptoms. Thus, while herpes viruses can enter both the lytic and lysogenic cycles, latency allows the virus to survive and evade detection by the immune system due to low viral gene expression. The model organism for studying lysogeny is the lambda ...
Latent viruses like CMV enter our bodies while we're young; after that, they establish a lifelong infection that researchers are only just beginning to understand.
Scientists are looking at reactivation of latent viruses, and other existing post-infection syndromes, for answers about long-haul COVID-19.
The relationship between the latent period, the infectious period (the period of communicability) and the incubation period. In some diseases, as depicted in this diagram, the latent period is shorter than the incubation period. A person can transmit an infection without showing any signs of the disease.