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The 3α-hydroxysteroid dehydrogenase (3α-HSD) enzyme is induced by certain (SSRIs), including fluoxetine, fluvoxamine, sertraline, and paroxetine, as well as by certain other antidepressants like venlafaxine and mirtazapine, and these antidepressants have been found to increase inhibitory neurosteroid levels.
Allopregnanolone is a naturally occurring neurosteroid which is made in the body from the hormone progesterone. [ 10 ] [ 11 ] As a medication, allopregnanolone is referred to as brexanolone , sold under the brand name Zulresso , [ 6 ] [ 12 ] and used to treat postpartum depression .
Allopregnanolone, a major endogenous inhibitory neurosteroid. Steroid ring system.. This is a list of neurosteroids, or natural and synthetic steroids that are active on the mammalian nervous system through receptors other than steroid hormone receptors.
An estimated 1 in 5 women struggle with perinatal mood and anxiety disorders after birth. ... The medication is a formulation of a neurosteroid called allopregnanolone and a “cousin” to the IV ...
Medications for Depression: An Overview. Antidepressants are a class of medications used very commonly to treat depression. In fact, nearly 13 percent of people 12 and over in the U.S. used ...
Antidepressants are most commonly prescribed for people who have major depressive disorder (MDD). MDD is described as feeling depressed, moody or sad all, every day, for at least two weeks.
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