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Megavitamin-B 6 syndrome is predominately a large fiber neuropathy characterized by sensory loss of joint position, vibration, and ataxia. [18] [26] Although it has characteristics of small fiber neuropathy in severe cases where there is impairment of pain, temperature, and autonomic functions. [62] [63] [14] [12] [59] [64] [17]
Nerve compression syndrome, or compression neuropathy, or nerve entrapment syndrome, is a medical condition caused by chronic, direct pressure on a peripheral nerve. [1] It is known colloquially as a trapped nerve , though this may also refer to nerve root compression (by a herniated disc , for example).
Neuropathic pain can occur alone or in combination with other types of pain. The identification of neuropathic pain components is important as different classes of analgesic are required. [7] The gold standard for diagnosing small fiber neuropathy as the etiology of neuropathic pain is skin biopsy.
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
[49] [50] This latter condition was later termed multifocal motor neuropathy [51] This distinction is important because multifocal motor neuropathy responds to intravenous immunoglobulin alone, while chronic inflammatory demyelinating polyneuropathy responds to intravenous immunoglobulin, steroids and plasma exchange. [52]
Image showing nerve conduction study which can measure nerve conduction velocity of peripheral nerves. The diagnosis of femoral neuropathy can be done through physical examinations, several imaging techniques and electrodiagnostic studies. [4] Provided patients do not suffer from haemorrhage, physical examinations is the first line of diagnosis ...
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